Computational Biologist and Bioinformatics Scientist
Company: Bevov
Location: Plano
Posted on: June 5, 2021
Job Description:
Job Description
We are seeking a talented and highly motivated
computational biologist and bioinformatics scientist to build and
enhance our client's drug positioning AI platform that can predict
drug response, therapeutic benefit and survival outcome of cancer
patients, and generate biomarkers for specific cancer types for a
drug candidate of interest. Candidates must have a passion to solve
world problems in cancer treatment using bioinformatics and
computer science with involvement in optimizing the company's core
bioinformatics workflows, computational algorithms, and AI-based
algorithms to improve their level of robustness, effectiveness, and
efficiency.
Responsibilities
- Leveraging cutting-edge Machine Learning technology to develop
clinically relevant AI platforms for discovery of
drug-tumor-specific biomarkers
- Designing biologically-meaningful optimization and validation
strategies to assess the applicability and relevance of the set of
biomarkers
- Applying biomarkers to larger data sets and developing optimal
approaches for patient stratification
- Incorporating multi-omics (RNAseq, NGS, proteomics, mutation,
methylation) data to the current workflow to strengthen the
platform
- Integrating systems biology and statistical analysis to
identify druggable tumor signaling pathways
- Assisting the data scientists to apply Machine Learning/Deep
Learning algorithms on biological data
- Identifying institutions/companies to collaborate with
and get data access
- Processing, analyzing, and interpreting high volumes of data
for the development and validation of methods
- Collaborating with other informatics scientists, academic
experts, and statisticians around data analysis methods and
solutions for automated workflows and database creation
- Implementing, executing, and documenting bioinformatics
pipelines and workflows
- Publishing scientific papers and posters and presenting the
platform and its findings effectively in conferences/meetings
Qualifications
- Ph.D. in Bioinformatics, Biostatistics, Computational Biology,
Computer Science or other related field or Masters degree with 3+
years of relevant experience
- At least 2-3 years of experience in scripting languages
like R, Perl & Python
- Solid understanding and 2+ years of hands-on experience
with statistics, data mining, machine learning, and statistical
data modeling techniques
- Familiarity with fundamental concepts in molecular biology,
chemical biology, statistics, and bioinformatics
- Acquiring a broad knowledge of multiple sectors in the life
sciences and NGS technology
- Experience using NGS data for one of the following:
biomarker discovery, drug target identification, large cohort
analysis, patient stratification
- Demonstrating technical and thought leadership and
ability to influence and guide the work of others
- Excellent interpersonal and communication skills, with
strong written and verbal presentation
- Background in oncology or clinical experience
- Familiarity with raw NGS data processing is highly
preferred
- Knowledge and experience of online bioinformatics analysis
tools & software
- Experience working with cloud computing
- Must be able to work in a fast-paced and team-oriented
environment
Benefits
Opportunity to work with a recent IPO company with a 10%
bonus based on performance and stock options. The company
provides multiple growth opportunities and as an early employee,
your work will have a direct impact on precision oncology that can
change the drug development and clinical trial model. In addition
to attractive compensation, and benefits, the company offer perks
like unlimited vacation/sick days, subsidized gym memberships, and
global travel opportunities to leading conferences and industry
trade show
Keywords: Bevov, Plano , Computational Biologist and Bioinformatics Scientist, Other , Plano, Texas
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